Tiamulin - MIB #74

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Date Revised: January 2017

Approved Brands

  1. Denagard Medicated Premix contains tiamulin base at 17.8 g/kg (equivalent to 22 g of tiamulin hydrogen fumarate per kg) (Elanco Canada Limited)
  2. Tiamulin 1.78% Premix contains tiamulin base at 17.8 g/kg (equivalent to 22 g of tiamulin hydrogen fumarate per kg) (Bio Agri Mix LP)
  3. Denagard 10% GF Premix contains tiamulin base at 80.91 g/kg (equivalent to 100 g of tiamulin hydrogen fumarate per kg) (Elanco Canada Limited)
  4. Tiamulin HF 10% Premix contains tiamulin base at 80.91 g/kg (equivalent to 100 g of tiamulin hydrogen fumarate USP at 100 g per kg) (Bio Agri Mix LP)

Approved for use

In meal or pellet feed for swine.

Approved claims

For swine - Claim 1, 2, 3, 4, and 5
Claim 1 and 2 - approved with the use of all Premixes.
Claim 3-4 and 5 - approved with the use of Denagard 10% GF Premix and Tiamulin HF 10% Premix.

Claim 1: For the prevention of swine dysentery associated with Brachyspira hyodysenteriae

Level of Drug:

31.2 mg/kg (0.00312%) of tiamulin base or 38.6 mg/kg (0.00386%) of tiamulin hydrogen fumarate in the complete feed.

Directions:

Feed continuously as the sole ration to swine on premises with a history of swine dysentery but where signs of the disease have not yet occurred. Feed continuously to prevent reinfection following use of tiamulin at 178.1 mg/kg for 14 days or following use of tiamulin medicated water for treatment of swine dysentery associated with Brachyspira hyodysenteriae.

Warning:

  1. Treated animals must not be slaughtered for use in food for at least two (2) days after the latest treatment with this medicated feed.
  2. Keep out of reach of children (required on premix and supplement labels only).

Caution:

  1. Swine being medicated with tiamulin should not have access to or be treated with tiamulin incompatible polyether ionophores (e.g., monensin, salinomycin, narasin, lasalocid and semduramicin).
  2. Use as the only source of tiamulin. Discontinue use if toxicity occurs.
  3. Do not use in feeds containing pellet-binding agents (required on premix and supplement labels only).
  4. Do not feed this medicated feed to gilts and sows during four weeks after service.
  5. Do not feed this medicated feed to animals other than swine.

Claim 2: For the treatment of swine dysentery associated with Brachyspira hyodysenteriae

Level of Drug:

178.1 mg/kg (0.01781%) of tiamulin base or 220.1 mg/kg (0.02201%) of tiamulin hydrogen fumarate in the complete feed.

Directions:

Feed continuously as the sole ration for 14 days.

Warning:

  1. Treated animals must not be slaughtered for use in food for at least seven (7) days after the latest treatment with this drug.
  2. Keep out of reach of children (required on premix and supplement labels only).

Caution:

  1. Swine being medicated with tiamulin should not have access to or be treated with tiamulin incompatible polyether ionophores (e.g.: monensin, salinomycin, narasin, lasalocid and semduramicin).
  2. Use as the only source of tiamulin. Discontinue use if toxicity occurs.
  3. Do not use in feeds containing pellet-binding agents (required on premix and supplement labels only).
  4. Do not feed this medicated feed to gilts and sows during four weeks after service.
  5. Do not feed this medicated feed to animals other than swine.

Adverse Reactions: (Not required on feed labels)

  1. Overdoses of tiamulin have sometimes produced transitory salivation, vomiting and an apparent calming effect on the pig. In very rare cases, death has been reported.
  2. In rare cases, redness of the skin, primarily over the ham and underline, has been observed during medication.
  3. If signs of toxicity or redness of skin occurs, promptly discontinue use of medicated feeds.

Note: (Required on feed labels)

During treatment, swine should be housed under conditions of adequate space and sanitation.

Claim 3: For the treatment of porcine colonic spirochaetosis (colitis) associated with Brachyspira pilosicoli.

Level of Drug:

178.1 mg/kg (0.01781%) of tiamulin base or 220.1 mg/kg (0.02201%) of tiamulin hydrogen fumarate in the complete feed.

Directions:

Feed continuously as the sole ration for 14 days.

Warning:

  1. Treated animals must not be slaughtered for use in food for at least seven (7) days after the latest treatment with this medicated feed.
  2. Keep out of reach of children. (Required on premix and supplement labels only.)

Caution:

  1. Swine being medicated with tiamulin should not have access to or be treated with tiamulin incompatible polyether ionophores (e.g.: monensin, salinomycin, narasin, lasalocid and semduramicin).
  2. Use as the only source of tiamulin. Discontinue use if toxicity occurs.
  3. Do not use in feeds containing pellet-binding agents. (Required on premix and supplement labels only.)
  4. Do not feed this medicated feed to gilts and sows during four weeks after service.
  5. Do not feed this medicated feed to animals other than swine.

Adverse Reactions: (Not required on feed labels)

  1. Overdoses of tiamulin have sometimes produced transitory salivation, vomiting and an apparent calming effect on the pig. In very rare cases, death has been reported.
  2. In rare cases, redness of the skin, primarily over the ham and underline, has been observed during medication.
  3. If signs of toxicity or redness of skin occurs, promptly discontinue use of medicated feeds.

Note: (Required on feed labels)

During treatment, swine should be housed under conditions of adequate space and sanitation.

Claim 4: For the treatment of porcine proliferative enteropathy (ileitis) caused by Lawsonia intracellularis.

Level of Drug:

121.4 mg/kg (0.01214%) of tiamulin base or 150 mg/kg (0.0150%) of tiamulin hydrogen fumarate in the complete feed.

Directions:

Feed continuously as the sole ration for 14 days.

Warning:

  1. Treated animals must not be slaughtered for use in food for at least seven (7) days after the latest treatment with this medicated feed.
  2. Keep out of reach of children. (Required on premix and supplement labels only.)

Caution:

  1. Swine being medicated with tiamulin should not have access to or be treated with tiamulin incompatible polyether ionophores (e.g.: monensin, salinomycin, narasin, lasalocid and semduramicin).
  2. Use as the only source of tiamulin. Discontinue use if toxicity occurs.
  3. Do not use in feeds containing pellet-binding agents. (Required on premix and supplement labels only.)
  4. Do not feed this medicated feed to gilts and sows during four weeks after service.
  5. Do not feed this medicated feed to animals other than swine.

Adverse Reactions: (Not required on feed labels)

  1. Overdoses of tiamulin have sometimes produced transitory salivation, vomiting and an apparent calming effect on the pig. In very rare cases, death has been reported.
  2. In rare cases, redness of the skin, primarily over the ham and underline, has been observed during medication.
  3. If signs of toxicity or redness of skin occurs, promptly discontinue use of medicated feeds.

Note: (Required on feed labels)

During treatment, swine should be housed under conditions of adequate space and sanitation.

Claim 5: For the treatment of enzootic pneumonia caused by Mycoplasma hyopneumoniae.

Level of Drug:

133.5 mg/kg (0.01335%) of tiamulin base or 165 mg/kg (0.0165%) of tiamulin hydrogen fumarate in the complete feed.

Directions:

Feed continuously as the sole ration for 14 days.

Warning:

  1. Treated animals must not be slaughtered for use in food for at least seven (7) days after the latest treatment with this medicated feed.
  2. Keep out of reach of children. (Required on premix and supplement labels only.)

Caution:

  1. Swine being medicated with tiamulin should not have access to or be treated with tiamulin incompatible polyether ionophores (e.g.: monensin, salinomycin, narasin, lasalocid and semduramicin).
  2. Use as the only source of tiamulin. Discontinue use if toxicity occurs.
  3. Do not use in feeds containing pellet-binding agents. (Required on premix and supplement labels only.)
  4. Do not feed this medicated feed to gilts and sows during four weeks after service.
  5. Do not feed this medicated feed to animals other than swine.

Adverse Reactions: (Not required on feed labels)

  1. Overdoses of tiamulin have sometimes produced transitory salivation, vomiting and an apparent calming effect on the pig. In very rare cases, death has been reported.
  2. In rare cases, redness of the skin, primarily over the ham and underline, has been observed during medication.
  3. If signs of toxicity or redness of skin occurs, promptly discontinue use of medicated feeds.

Note: (Required on feed labels)

During treatment, swine should be housed under conditions of adequate space and sanitation.

Accepted Compatibilities

Tiamulin is compatible with the following drugs. For further details refer to the MIB as indicated.

MIB
#
Medicated ingredients For use in feed for
34 Chlortetracycline hydrochloride swine
Date modified: